by Jeffrey T. Kirchner, DO, AAHIVS, AAHIVM Chief Medical Officer
March 17, 2020
Ghanem, KG et al. The Modern Epidemic of Syphilis.
N Engl J Med 2020; 382:845-854. DOI: 10.1056/NEJMra190159
With the continued increase in STIs seen in the U.S. over the past few years, I have decided to cite an excellent review article on Syphilis and have included- several key points below.
I would strongly encourage review of the full content of the cited article. Syphilis screening at least annually is recommended for the majority of our HIV-infected patients as well as those on PrEP. Fortunately, PCN remains highly effective as primary treatment. There remains nuances regarding follow-up titers including a discussion regarding the need for CSF analysis via LP, “sero-fast” status and what constitutes treatment failure (this is rare).
The author has no conflicts of interest to disclose.
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