CLINICAL RESEARCH UPDATE

The American Academy of HIV Medicine’s “Clinical Research Update” features clinical information from Carolyn Chu, MD, MSc, AAHIVS who serves as chief medical officer for the Academy. Dr. Chu provides a short synopsis of key clinical studies, reviews, and clinical practice guidelines selected on the basis of having immediate or important clinical implications for our Academy members and their patients. Periodic updates from the U.S. Department of Health and Human Services (DHHS) HIV Clinical Practice Guidelines are also included.

Clinical Research Update 9.10.24 – Implementation of Single High-dose Liposomal Amphotericin B Based Induction Therapy for Treatment of HIV-associated Cryptococcal Meningitis in Uganda

Clinical Research Update 8.27.24 – Health, Access to Care, and Financial Barriers to Care Among People Incarcerated in U.S. Prisons

Clinical Research Update 8.13.24 – PrEP Use in a U.S. National Sample of Trans Men and Other Trans Masculine Men Who Have Sex with Men: A Longitudinal Analysis

Clinical Research Update 7.16.24 – A Systematic Review and Meta-analysis of the Risk of Hepatitis B Virus (HBV) Resistance in People Treated with entecavir or tenofovir

Clinical Research Update 7.2.24 – Characterizing HIV Drug Resistance in Cases of Vertical Rransmission in the VESTED Randomized Antiretroviral Treatment Trial

Clinical Research Update 6.18.24 – Chronic Liver Enzyme Elevation and Use of Contemporary ARVs Among Persons with HIV

Clinical Research Update 6.4.24 – Dolutegravir plus boosted darunavir vs recommended standard-of-care antiretroviral regimens in PWH for whom recommended first-line non-nucleoside reverse transcriptase inhibitor therapy has failed (D2EFT)

Clinical Research Update 5.21.24 – Prevalence of Anal HPV Infection and Anal HSIL Among MSM 50 Years and Older Living With or Without HIV

Clinical Research Update 5.7.24 – The Effect of Open-label Semaglutide on Metabolic Dysfunction-associated Steatotic Liver Disease in People with HIV

Clinical Research Update 4.23.24 – Acceptability and Tolerability of Long-acting Injectable cabotegravir or rilpivirine in the First Cohort of Virologically Suppressed Adolescents Living with HIV

Clinical Research Update 4.9.24 – The Hepatitis C Care Cascade in California State Prisons: Screening and Treatment Scale-up and Progress Toward Elimination

Clinical Research Update 3.26.24 – Point of Care Testing for Hepatitis C in the Priority Settings of Mental Health, Prisons and Drug and Alcohol Facilities

Clinical Research Update 3.12.24 – Effects of Preterm Birth, Maternal ART and Breastfeeding on 24-month Infant HIV-free Survival in a Randomized Trial

Clinical Research Update 2.27.24 – Virology and Surveillance; Risk Assessment and Policy Subgroups of the ISBT Working Party on Transfusion-transmitted Infectious Diseases

Clinical Research Update 2.13.24 – Cost Analysis of Implementing a 12-Month Recertification Criterion for Ryan White HIV/AIDS Program’s AIDS Drug Assistance Program in Washington State

Clinical Research Update 1.30.24 – Optimal Hepatitis C Treatment Adherence Patterns and Sustained Virologic Response Among People Who Inject Drugs: THE HERO Study

Clinical Research Update 1.16.24 – Common Antiretroviral Combinations are Associated with Somatic Depressive Symptoms in Women with HIV

Clinical Research Update 1.2.24 – Doxycycline Prophylaxis to Prevent STIs in Women; dPEP Kenya Study Team

Clinical Research Update 12.19.23 – Reflex HIV-1 RNA Testing Enables Timely Differentiation of False Positive Results from Acute HIV Infection

Clinical Research Update 12.5.23 – Outcomes of Bariatric Surgery in People with HIV

Clinical Research Update 11.21.23 – Weight Loss Associated with semaglutide Treatment Among People with HIV

Clinical Research Update 11.7.23 – Outcomes and Predictors of Rapid Antiretroviral Therapy Initiation for People with Newly Diagnosed HIV in an Integrated Health Care System

Clinical Research Update 10.24.23 – Bictegravir/emtricitabine/tenofovir alafenamide in Pediatrics: Real-life Experience from a French Cohort

Clinical Research Update 10.10.23 – Adverse Pregnancy Outcomes Among HIV-infected Women Taking Isoniazid Preventive Therapy During the First Trimester

Clinical Research Update 9.26.23 – Switching to BIC/FTC/TAF Plus darunavir/cobicistat in Heavily Antiretroviral-experienced, Virologically Suppressed Adults with HIV Receiving Complex Regimens

Clinical Research Update 9.12.23 – Increase in False-positive Fourth-generation HIV Tests in Patients with Coronavirus

Clinical Research Update 8.29.23 – Racial Disparities in Access to the Kidney Transplant Waitlist Among People with HIV

Clinical Research Update 8.15.23 – Doravirine/lamivudine/tenofovir disoproxil fumarate for Nonoccupational HIV-1 PrEP: A Prospective Open-label Trial (DORAVIPEP)

Clinical Research Update 8.1.23 – Efficacy and Safety of the Novel Capsid Inhibitor lenacapavir to Treat Multidrug-resistant HIV

Clinical Research Update 7.18.23 – Assessing the Virologic Impact of Archived Resistance in the dolutegravir/lamivudine 2-drug regimen HIV-1 switch study TANGO through Week 144

Clinical Research Update 6.20.23 – Comparing 7 vs. 6-8 day Penicillin Treatment Intervals Among Pregnant People with Syphilis of Late or Unknown Duration

Clinical Research Update 6.6.23 – Standard-dose vs. Double-dose dolutegravir in HIV-associated Tuberculosis in South Africa

Clinical Research Update 5.23.23 – Estimated Effectiveness of JYNNEOS Vaccine in Preventing Mpox

Clinical Research Update 5.9.23 – Prostate Cancer in Transgender Women in the Veterans Affairs Health System

Clinical Research Update 4.25.23 – Biologic Therapies in HIV/AIDS Patients with Inflammatory Diseases

Clinical Research Update 4.11.23 – Immunogenicity and safety of Hepatitis B vaccine with a Toll-like Receptor 9 Agonist Adjuvant (HEPLISAV-B) in HBV Vaccine-naïve People with HIV

Clinical Research Update 3.28.23 – Pregnancy and Neonatal Safety Outcomes of Timing of Initiation of Daily Oral tenofovir disoproxil fumarate and emtricitabine PrEP for HIV prevention

Clinical Research Update 3.14.23 – Residents and Fellows’ Confidence in Prescribing PrEP

Clinical Research Update 2.28.23 – Single-center Experience Evaluating and Initiating PWH on Long-acting cabotegravir/rilpivirine

Clinical Research Update 2.14.23 – Pharmacokinetics, tolerability, and safety of doravirine and doravirine/lamivudine/tenofovir disoproxil fumarate fixed-dosed combination tablets in adolescents with HIV

Clinical Research Update 1.31.23 – Evaluation of Treatment Simplification Strategies in People with HIV with Multi-drug Resistance

Clinical Research Update 1.17.23 – Long-term Persistence of HCV Resistance-associated Substitutions After DAA Treatment Failure

Clinical Research Update 1.3.23 – Performance of Cardiovascular Risk Prediction Models Among People with HIV: A Systematic Review and Meta-analysis

Clinical Research Update 12.20.22 – Resilience and Optimism as Moderators of the Negative Effects of Stigma on Women with HIV

Clinical Research Update 12.6.22 – Transfer of Antiretroviral Drugs into Breastmilk: A Prospective Study from the Swiss Mother and Child HIV Cohort Study

Clinical Research Update 11.22.22 – Utilization of bictegravir/emtricitabine/tenofovir alafenamide in patients with end-stage renal disease on hemodialysis

Clinical Research Update 11.8.22 – Prevention and Care Opportunities for People Who Inject Drugs in an HIV Outbreak 

Clinical Research Update 10.25.22 – CoRIS and CoRISpe Spanish National Cohorts, Integrase inhibitors in children and adolescents: clinical use and resistance

Clinical Research Update 10.11.22 – Impact on Renal Function of Daily and On-demand HIV PrEP in the ANRS-PREVENIR Study

Clinical Research Update 9.27.22 – Use and safety of appearance and performance enhancing supplements in gay, bisexual, and other MSM receiving daily tenofovir disoproxil fumarate/emtricitabine as HIV PrEP

Clinical Research Update 9.13.22 – Update of perinatal HIV-1 transmission in France: zero transmission for 5482 mothers on continuous ART from conception and with undetectable viral load at delivery

Clinical Research Update 8.30.22 – Recent abacavir use and incident cardiovascular disease in contemporary treated people living with HIV

Clinical Research Update 8.16.22 – Compassionate use of long-acting cabotegravir plus rilpivirine for PLWH in need of parenteral antiretroviral therapy

Clinical Research Update 8.2.22 – Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK

Clinical Research Update 7.19.22 – Risks and benefits of oral HIV PrEP for people with chronic hepatitis B

Clinical Research Update 7.5.22 – Adverse effects of testosterone use among men living with HIV: Data from the PUSH! study

Clinical Research Update 6.21.22 – The effect of menopausal status, age, and HIV on non-AIDS comorbidity burden among U.S. women

Clinical Research Update 6.7.22 – Baseline HIV drug-resistance testing: 12 U.S. jurisdictions, 2014-2019

Clinical Research Update 5.24.22 – Retreatment for HCV direct acting antiviral therapy virological failure in primary and tertiary settings: the REACH-C cohort

Clinical Research Update 5.10.22 – Direct and indirect effects of a Project ECHO longitudinal clinical tele-mentoring program on viral suppression for persons with HIV: a population-based analysis

Clinical Research Update 4.26.22 – A systematic review of factors critical for HIV health literacy, ART adherence and retention in care in the U.S. for racial and ethnic minorities

Clinical Research Update 4.12.22 – Essential elements of and challenges to rapid ART implementation: a qualitative study of three programs in the United States

Clinical Research Update 3.29.22 – Characterization of HIV infections in women who received injectable cabotegravir or tenofovir disoproxil fumarate/emtricitabine for HIV prevention

Clinical Research Update 3.15.22 – Method of calculating renal function estimates could inappropriately exclude transgender patients receiving gender-affirming hormone therapy from PrEP eligibility

Clinical Research Update 3.1.22 – UK Guideline for the Use of HIV Post-exposure Prophylaxis 2021

Clinical Research Update 2.15.22 – 4-days-on and 3-days-off Maintenance Treatment Strategy for Adults with HIV

Clinical Research Update 2.1.22 – A Minimal Monitoring Approach for the Treatment of HCV Infection

Clinical Research Update 1.18.22 – The Effect of Initial Patient Experiences and Life Stressors on Predicting Lost to Follow-Up in Patients New to an HIV Clinic

Clinical Research Update 1.4.22 – Acceptability of HIV testing for adolescents and young adults by delivery model

Clinical  Research Update 1.4.22 – HIV-associated wasting prevalence in the era of modern antiretroviral therapy

Clinical Research Update 12.28.21 – Rising Rates of Recent PrEP Exposure Among MSM Newly Diagnosed with HIV: Antiviral Resistance Patterns and Treatment Outcomes

Clinical Research Update 12.14.21 – Experience and Outcomes of Breastfed Infants of Women with HIV in the United States

Clinical Research Update 11.30.21 – Science Over Stigma: Lessons and Future Direction of HIV-to-HIV Transplantation

Clinical Research Update 11.16.21 – Rilpivirine plus cobicistat-boosted darunavir as alternative to standard three-drug therapy in HIV-infected, virologically suppressed subjects: Final results of the PROBE 2 trial

Clinical Research Update 11.2.21 – Perinatal Depressive Symptoms, HIV Suppression, and the Underlying Role of ART Adherence: A Longitudinal Mediation Analysis in the IMPAACT P1025 Cohort

Clinical Research Update 10.19.21 – Dolutegravir-based dual maintenance regimens combined with lamivudine/emtricitabine or rilpivirine: risk of virological failure in a real-life setting

Clinical Research Update 10.5.21 – Safety of tenofovir alafenamide in PWH who experienced proximal renal tubulopathy on tenofovir disoproxil fumarate

Clinical Research Update 9.21.21 – DTG/3TC as a first-line regimen in a test-and-treat setting for newly diagnosed PWH

Clinical Research Update 9.7.21 – Maternal HIV drug resistance is associated with vertical transmission and is prevalent in infected infants

Clinical Research Update 8.24.21 – Impact of depression and post-traumatic stress symptoms on physical health perceptions and functional impairment among sexual minority men with HIV with histories of trauma

Clinical Research Update 8.10.21 – Incident Bone Fracture and Mortality in Large HIV Cohort Outpatient Study

Clinical Research Update 7.27.21 – Pharmacokinetics of bictegravir and tenofovir in combination with darunavir/cobicistat in treatment-experienced PWH

Clinical Research Update 7.13.21 – Forgiveness of Dolutegravir-based Triple Therapy Compared to Older ARV Regimens

Clinical Research Update 6.29.21 – The Effect of Buprenorphine on HIV Viral Suppression

Clinical Research Update 6.15.21 – To Dose-adjust or Not to Dose-adjust: Lamivudine Dose in Kidney Impairment

Clinical Research Update 6.1.21 – Sofosbuvir/velpatasvir for 12 vs. 6 Weeks for the Treatment of Recently Acquired HCV

Clinical Research Update 5.18.21 – Frequency of high grade squamous cervical lesions among women over age 65 years living with HIV

Clinical Research Update 5.4.21 – The Role of Pharmacies in the HIV Prevention and Care Continuums: A Systematic Review

Clinical Research Update 4.20.21 – Pregnancy in an Urban Cohort of Adolescents Living with HIV: Characteristics and Outcomes in Comparison to Adults

Clinical Research Update 4.6.21 – Toward Safer Opioid Prescribing: Effects of the TOWER Intervention on HIV Care Providers

Clinical Research Update 3.23.21 – Prevalence of Self-report Neurologic and Ocular Symptoms in Early Syphilis Cases

Clinical Research Update 3.9.21 – Heplisav-B Seroprotection in People with HIV: A Single-Center Experience

Clinical Research Update 2.23.21 – Interventions to Improve HIV Care Continuum Outcomes Among Individuals Released from Prison or Jail

Clinical Research Update 2.9.21 – Risk of Smoking-related Cancers Among Women and Men Living With and Without HIV

Clinical Research Update 1.26.21 – Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine and the BNT162b2 mRNA Covid-19 Vaccine

Clinical Research Update 12.29.20 – NIH Workshop on HIV-Associated Comorbidities, Coinfections, and Complications: Summary and Recommendation for Future Research

Clinical Research Update 12.22.20 – Risk Factors for Weight Gain Following Switch to Integrase Inhibitor-Based Antiretroviral Therapy

Clinical Research Update 12.15.20 – Tenofovir Alafenamide vs. Tenofovir Disoproxil Fumarate

Clinical Research Update 12.8.20 – COVID-19 Related Medical Mistrust, Health Impacts, and Potential Vaccine Hesitancy Among Black Americans Living with HIV

Clinical Research Update 12.1.20 – Outcomes of Coronary Artery Bypass Grafting in Patients with HIV

Clinical Research Update 11.24.20 – Evolution of Drug Interactions with Antiretroviral Medication in People with HIV

Clinical Research Update 11.17.20 – Surprisingly Low Levels of Measles Immunity in Persons With HIV: A Seroprevalence Survey in a United States HIV Clinic

Clinical Research Update 11.10.20 – Safety and Efficacy of the HIV-1 Attachment Inhibitor Prodrug Fostemsavir in Heavily Treatment-Experienced Individuals: Week 96 Results of the Phase 3 BRIGHTE Study

Clinical Research Update 11.3.20 – Virological Failure and Acquired Genotypic Resistance Associated with Contemporary Antiretroviral Treatment Regimens

Clinical Research Update 10.27.20 – Characteristics, Comorbidities, and Outcomes in a Multicenter Registry of Patients with HIV and Coronavirus Disease-19

Clinical Research Update 10.20.20 – ART Drugs for Treatment and Prevention of HIV Infection in Adults: 2020 Recommendations of the ISA–USA Panel

Clinical Research Update 10.13.20 – Structural and Functional Brain Abnormalities in HIV Disease Revealed by Multimodal MRI Fusion: Association with Cognitive Function

Clinical Research Update 10.6.20 – Frailty Is Associated with Mortality and Incident Comorbidity Among Middle-Aged HIV-Positive and HIV-Negative Participants

Clinical Research Update 9.29.20 – Screening & Enrollment by Sex in HIV Clinical Trials in the United States

Clinical Research Update 9.22.20 – Prevalence of Hepatitis A Immunity and Decision-tree analysis Among Men Who Have Sex With Men and are Living With HIV in Tokyo

Clinical Research Update 9.15.20 – Prospective International Study of Incidence and Predictors of Immune Reconstitution Inflammatory Syndrome and Death in People Living with HIV and Severe Lymphopenia

Clinical Research Update 9.8.20 – Trends in Time from HIV Diagnosis to First Viral Suppression Following Revised U.S. HIV Treatment Guidelines, 2012–2017

Clinical Research Update 9.1.20 – Outcomes Among HIV-Positive Patients Hospitalized With COVID-19

Clinical Research Update 8.25.20 – Rapid antiretroviral therapy among individuals with acute and early HIV

Clinical Reserach Update 8.18.20 – HIV infection is associated with lower risk of hepatocellular carcinoma after sustained virological response to direct-acting antivirals in HCV infected-patients with advanced fibrosis

Clinical Research Update 8.11.20 – Deaths attributable to cancer in the United States HIV population during 2001-2015

Clinical Research Update 8.4.20 – AIDS 2020 Highlights – Part Four

Clinical Research Update 7.28.20 – AIDS 2020 Highlights – Part Three

Clinical Research Update 7.21.20 – AIDS 2020 Highlights – Part Two

Clinical Research Update 7.14.20 – AIDS 2020 Highlights – Part One

Clinical Research Update 7.7.20 – Distal Sensory Peripheral Neuropathy in HIV Type 1– Positive Individuals Before and After Antiretroviral Therapy Initiation in Diverse Resource-Limited Settings

Clinical Research Update 6.30.20 – Initiation of ART in the Hospital is Associated with Linkage to HIV Care for Persons with HIV and Substance Use

Clinical Research update 6.23.20 – Integrase Strand Transfer Inhibitors are associated with lower risk of incident Cardiovascular Disease in People Living with HIV

Clinical Research Update 6.16.20 – The Natural History of Anal High-grade Squamous Intraepithelial Lesions in Gay and Bisexual Men

Clinical Research Update 6.9.20 – The HIV Outpatient Study—25 Years of HIV Patient Care and Epidemiologic Research

Clinical Research Update 6.2.20 – Recurrence and Occurrence of Kaposi’s Sarcoma in Patients Living with HIV and on Antiretroviral Therapy, despite Suppressed HIV Viremia

Clinical Research Update 5.26.20 (CROI 2020) – Changes in Body Mass Index and the Risk of Cardiovascular Disease: The D:A:D Study

Clinical Research Update 5.19.20 (CROI 2020) – Trends in HIV Drug Resistance in the United States

Clinical Research Update 5.12.20 (CROI 2020) – 144-Week Efficacy and Safety of B/F/TAF in Treatment-Naive Adults ≥50 Years

Clinical Research Update 5.5.20 (CROI 2020) – Increased Overall Life Expectancy but Not Comorbidity-free Years for People with HIV

Clinical Research Update 4.28.20 (CROI 2020) – HIV Viral Blips in Adults Treated with INSTI-based Regimens through 144 weeks

Clinical Research Update 4.21.20 (CROI 2020) – Long-Acting Cabotegravir + Rilpivirine for HIV Treatment: FLAIR Week 96 Results

Clinical Research Update 4.14.20 (CROI 2020) – Safety and Efficacy of Dolutegravir vs Efavirenz and Tenofovir Disoproxil Fumarate vs Tenofovir Alafenamide in Pregnancy: IMPAACT 2010 Trial

Clinical Research Update 4.7.20 (CROI 2020) – Cabotegravir + Rilpivirine every 2 Months is Non-Inferior to Monthly: ATLAS-2M Study

Clinical Reseach Update 3.31.20 – Elvitegravir-Cobicistat-Emtricitabine-Tenofovir Alafenamide Single-tablet Regimen for HIV Postexposure Prophylaxis

Clinical Research Update 3.24.20 – Long-Acting Cabotegravir and Rilpivirine for Maintenance of HIV-1 Suppression

Clinical Research Update 3.17.20 – The Modern Epidemic of Syphilis

Clinical Research Update 3.10.20 – Outcomes in Human Immunodeficiency Virus-Infected Recipients of Heart Transplants

Clinical Research Update 3.3.20 – Dolutegravir- based Antiretroviral Therapy for Patients Coinfected with Tuberculosis and HIV

Clinical Research Update 2.25.20 – Adherence and Viral Suppression among Participants of the Patient-centered HIV Care Model Project: A Collaboration Between Community-based Pharmacists and HIV Clinical Providers

Clinical Research Update 2.18.20 – Atherosclerotic Cardiovascular Disease Risk Profile of Tenofovir Alafenamide versus Tenofovir Disoproxil Fumarate

Clinical Research Update 2.11.20 – HIV and Hepatitis C Virus Infection Testing Among Commercially Insured Persons Who Inject Drugs

Clinical Research Update 2.4.20 – Week 96 results of a phase 3 trial of D/C/F/TAF in treatment-naïve HIV-1 patients.

Clinical Research Update 1.28.20 – Clinical and Economic Impact of Ibalizumab for People with Multidrug-Resistant HIV in the United States

Clinical Research Update 1.21.20 – Accuracy in self-report of viral suppression among HIV-positive men with HIV-negative male partners

Clinical Research Update 1.14.20 – Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in a Rapid Initiation Model of Care for HIV-1 Infection: Primary Analysis of the DIAMOND Study

Clinical Research Update 1.7.20 – Effect of Cannabis Use on HIV DNA during Suppressive Antiretroviral Therapy

Clinical Research Update 12.17.10 – Nonadherence to Any Prescribed Medication Due to Costs among Adults with HIV Infection

Clinical Research Update 12.10.19 – Female genital tract shedding of HIV-1 is rare in women with suppressed HIV-1 in plasma

Clinical Research Update 12.3.19 – Use of Contemporary Protease Inhibitors and Risk of Incident Chronic Kidney Disease in Persons with HIV: The D:A:D Study

Clinical Research Update 11.26.19 – Switching to Fixed-Dose Bictegravir, Emtricitabine, and Tenofovir Alafenamide (B/F/TAF) in Virologically Suppressed HIV-1 Infected Women

Clinical Research Update 11.19.19 – Effect of daily consumption of extra virgin olive oil on the lipid profile and microbiota of HIV-infected patients over 50 years of age

Clinical Research Update 11.12.19 – Changes in Body Mass Index and Atherosclerotic Disease Risk Score After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide

Clinical Research Update 11.5.19 – Noninferiority of simplified dolutegravir monotherapy compared to continued combination antiretroviral therapy that was initiated during primary HIV infection: A randomized, controlled, multisite, open-label noninferiority trial. 

Clinical Research Update 10.29.19 – Lipid management for the Prevention of Atherosclerotic Heart Disease

Clinical Research Update 10.22.19 – Use of Recommended Preventive Health Care Services and Variations in HIV Care among Women with HIV in the United States

Clinical Research Update 10.15.19 – Frailty Is an Independent Risk Factor for Mortality, Cardiovascular Disease, Bone Disease, and Diabetes Among Aging Adults with Human Immunodeficiency Virus

Clinical Research Update 10.8.19 – Association of Human Immunodeficiency Virus Infection and Risk of Peripheral Artery Disease

Clinical Research Update 10.1.19 – Non-AIDS comorbidity burden differs by sex, race, and insurance type in aging adults in HIV care.

Clinical Research Update 9.24.19 – Weight gain associated with Integrase Stand Transfer Inhibitor use in women

Clinical Research Update 9.17.19 – Serious clinical events in HIV-positive persons with chronic kidney disease

Clinical Research Update 9.10.19 – Update to the Varicella-Zoster Virus (VZV) Disease Section of the DHHS Adult and Adolescent Opportunistic Infections Guidelines

Clinical Research Update 9.3.19 – Renal safety of tenofovir alafenamide vs. tenofovir disoproxil fumarate: a pooled analysis of 26 clinical trials

Clinical Research Update 8.27.19 – Increased risk of anemia, neutropenia and thrombocytopenia in people with HIV and well-controlled viral replication

Clinical Research Update 8.20.19 – Alopecia After Switch to Tenofovir Alafenamide in 6 African American Women

Clinical Research Update 8.13.19 – Low level viremia and virologic failure in persons with HIV infection treated with antiretroviral therapy

Clinical Research Update 8.6.19 – Generalized anxiety disorder symptoms among persons with diagnosed HIV in the United States

Clinical Research Update 7.30.19 – Long-term evolution of CD4+cell count in patients under combined antiretroviral therapy

Clinical Research Update 7.23.19 – Durability of dolutegravir plus boosted darunavir as salvage or simplification of salvage regimens in HIV-1 infected, highly treatment-experienced individuals

Clinical Research Update 7.16.19 – Nonadherence and unsuppressed viral load across adolescence among US youth with perinatally acquired HIV

Clinical Research Update 7.9.19 – Herpes Zoster rates continue to decline in people living with HIV but remain higher than rates reported in the general US Population.

Clinical Research Update 7.2.19 – Pregnancy and Neonatal Outcomes Following Prenatal Exposure to Dolutegravir

Clinical Research Update 6.25.19 – Colorectal Cancer Screening in People With and Without HIV in an Integrated Health Care Setting

Clinical Research Update 6.18.19 – The benefit of immediate compared with deferred antiretroviral therapy on CD4+ cell count recovery in early HIV infection

Clinical Research Update 6.11.19 – Bictegravir combined with emtricitabine and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection: Week 96 results from a randomized, double-blind, multicenter, phase 3, non-inferiority trial

Clinical Research Update 5.30.19 – Clinical impact and cost-effectiveness of genotype testing at HIV diagnosis in the United States

Clinical Research Update 5.23.19 – Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy

Clinical Research Update 5.16.19 – Sexually Acquired Hepatitis C Infection in HIV-Uninfected Men Who Have Sex with Men Using Preexposure Prophylaxis Against HIV

Clinical Research Update 5.9.19 – Differences by Sex in Cardiovascular Comorbid Conditions Among Older Adults Receiving HIV

Clinical Research Update 5.2.19 – Characterizing the HIV Care Continuum among Transgender Women and Cisgender Women and Men in Clinical Care

Clinical Research Update 4.18.19 – Association of PrEP with Incidence of STIs Among High Risk Individuals

Clinical Research Update 4.11.19 – Short Physical Performance Battery (SPPB)

Clinical Research Update 4.4.19 – What’s New in the DHHS Guidelines?